One of many naturally occurring cannabinoids in cannabis plants is cannabidiol (CBD). Some persons with chronic pain manage their symptoms by using topical CBD creams or CBD oil to their skin. CBD oil may ease pain associated with a range of medical disorders by reducing inflammation or general discomfort. Among other things, joint discomfort, muscle pain, and pain from rheumatoid arthritis have all been issues for many of our customers.
Unfortunately, further research is required to confirm the pain-relieving advantages of CBD oil because of prohibitions on cannabis testing. The study on CBD products and pain management, however, has been encouraging. Importantly, research indicates that CBD may provide an alternative for patients who require long-term pain management and depend on drugs (like opioids) that may have harmful and habit-forming side effects.
Cannabidiol, or CBD, is a chemical substance that is found naturally in Cannabis sativa, the hemp plant. To give a variety of benefits, it can be consumed orally (as a tablet, capsule, or gummy), sublingually (under the tongue as a tincture), or topically (applied to the skin as a cream).
Most crucially, as long as the industrial hemp strain is EU-approved and free of THC, CBD, also known as cannabidiol, is lawful in the UK. Above all, you must ensure that you are purchasing it from a reputable source. Hemp certified by the EU is used to manufacture HempWell organic CBD, which is then processed and lab-verified to ensure its purity and dosage accuracy. From seed to shelf, we manage the process so you can be sure you’re getting a high-quality, completely traceable product. Read our Is CBD Legal? topic in the Education Center for additional details on CBD laws in the UK.
The endocannabinoid receptor system, a complex network of neurotransmitters and cannabinoid receptors, is found in the human body (ECS). According to research, the ECS and cannabinoids may be involved in a variety of physiological functions, and cannabinoid receptors are present in the skin.
How does CBD function?
Going over some fundamental biological concepts will help you grasp how CBD works.
First, neurotransmitters and neuromodulators, two classes of molecules, are abundant in the human nervous system. These are organic substances that our body employs to facilitate nerve cell communication. Additionally, only a select few “receptors”—proteins in nerve cells intended to trigger a reaction when they detect a neurotransmitter—interact with each neurotransmitter. This reaction can either promote nerve cell firing (known as agonists) or inhibit it (known as antagonists). Approximately 60 distinct neurotransmitters are known at this time. A neurotransmitter and each of its corresponding receptors are referred to together as a “system” by scientists. The adrenaline system, which originates around the kidneys and influences the brain’s “fight-or-flight” response, is definitely something you’ve heard of. The endocannabinoid system is the system that CBD can affect.
System of Endocannabinoids
Simply explained, endocannabinoids are cannabinoids (a particular group of neurotransmitters) that are produced by our body on a natural basis (Endo is latin for internal). The endocannabinoid system performs a unique purpose to control particular behaviors under normal circumstances, much like any other system. According to research, the endocannabinoid system is at least partially responsible for a wide range of behaviors, such as:
- Mood Appetite, among others. Additionally, it has been demonstrated that the endocannabinoid system influences pre-and postnatal development, as well as fertility and pregnancy.
Anandamide was the first endocannabinoid to be identified. Normally, a system’s receptors only interact with a particular neurotransmitter because the receptor is physically designed so that only the intended neurotransmitter would ‘fit’ in it. However, occasionally we discover additional substances that are sufficiently similar chemically to “fit” in the same way. One of those substances is CBD.
Cannabidiol, sometimes known as CBD, is a phytocannabinoid (a cannabinoid found in plants). Cannabidiol interacts with cannabinoid receptors as an antagonist of one cannabinoid receptor (CNR1) and as an agonist of another (CNR2) because its chemical structure is close enough to that of endocannabinoids.
Future Research Topics
Preliminary research have revealed that CNR2 aids in the regulation of immunological response, brain function, and the gastrointestinal system. Unfortunately, there isn’t enough information to conclusively state the effects of CBD on their own. Many claim that this interaction has an impact on levels of tension and anxiety as well as muscle relaxation from a layperson’s perspective. It has been suggested that the presence of cannabinoid receptors outside of the central nervous system, in and surrounding numerous other organs, is what causes CBD to have pain-relieving effects.
At this time, most of the known details of how CBD works in the body are speculative. Unfortunately, there is a dearth of research on CBD alone because the CBD market is still a young one. Thankfully, CBD’s rapid global uptake and growth will undoubtedly spur additional research, allowing us to better understand how CBD appears to function. Until then, we advise anyone looking to control their anxiety to speak with a doctor, counselor, or therapist to see whether CBD is the best treatment for them. Please let us know via email or review if you’re a CBD user who has had success using CBD to reduce pain and increase mobility. We’re always delighted to learn how our hemp has aided in healing!
Pain and CBD
Every person goes through periods of pain throughout their lives. Living with chronic pain can be difficult at best or incapacitating at worst. Opioids are frequently used to alleviate pain, but they are habit-forming and have dangerous adverse effects, therefore people are searching for alternatives everywhere. The US Center for Disease Control has declared the opioid overdose death epidemic (CDC). An opioid was a factor in more than 70% of drug-related deaths in the USA in 2019. It makes sense that more people are looking for alternatives to traditional painkillers.
Some people think CBD works well to ease the pain. The results of the research on CBD products and pain relief are encouraging. Due to constraints on the use of and study of cannabis, there are few human studies on CBD and pain, and more research is required in this field. However, the research we do have yields some positive findings. The results of the first human experimental investigation on CBD’s effects on pain demonstrated that people can actually experience significant pain relief from CBD. At first, scientists believed that CBD’s ability to reduce pain was just a placebo effect. But further research showed that CBD actually has pharmacological properties that reduced pain. We discovered improvements in pain measurements brought on by the pharmacological effects of CBD, which was very astounding and unexpected, according to lead researcher Martin De Vita. (Source)
Using CBD to Reduce Pain
To consume CBD for pain relief, there are numerous options: using a capsule, tablet, or gummy to take it in. After being digested, they are absorbed through the bloodstream, which can take up to two hours. A CBD oil can also be used to absorb CBD sublingually (under the tongue). You’ll see results more quickly and more of the CBD is preserved by letting the product absorb under your tongue.
By “topically,” we mean “made to be administered topically.” Topicals are an excellent option for relieving localized pain because CBD creams are designed to be absorbed into the skin. This is how CBD can be used to treat arthritis and joint pain. The physical motion of massaging the cream in may have additional advantages if you are treating a sore location. It is worthwhile to read our post on dosage information if you are unsure about how much to take.
Arthritis and CBD
It is generally recognized that cannabinoids are effective anti-inflammatory drugs (Source), and as a result, they may offer significant advantages in reducing the swelling, pain, and inflammation frequently linked to arthritis.
According to Arthritis.org, while animal studies have indicated that CBD has pain-relieving and anti-inflammatory qualities, quality human studies have not supported these claims. Anecdotally, some but not all patients with arthritis who have used CBD report observable pain relief, improved sleep, and/or decreased anxiety.
In 2016, a study on rats found that CBD treatment considerably reduced both arthritis pain and inflammation, while in 2018, a study on dogs with osteoarthritis showed that CBD treatment dramatically reduced pain and increased activity in the dogs examined. We anticipate seeing the outcomes of studies examining CBD’s potential to treat arthritis in human patients shortly, as there are currently more than 30 clinical trials being conducted in Europe for a variety of illnesses.
Athletes and Pain
Exercise places a lot of stress on our bodies, which can have both positive and bad effects. This is not surprising. Stress from training can boost performance (such the ability to lift more weight or run farther), but it can also cause injuries and suffering due to physical strain and long-term wear and tear. Athletes are turning to CBD in search of alternative pain relief and efficient sports recovery, but how can it help?
If you exercise frequently, you’ve certainly encountered a situation where you needed pain relief—whether it was because of an injury or for another reason. Athletes may gain from CBD’s pain-relieving properties if ingested since both preclinical and clinical research have suggested a possible benefit of its use in chronic pain (Source). As a result of the increased risk of gastrointestinal trauma, several over-the-counter painkillers known as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)—ibuprofen being one such example—can actually be harmful to athletes, especially ultra-distance athletes. This can include potentially fatal situations like upper GI bleeding or relatively mild dyspepsia. Source. It is not surprising that athletes are seeking out non-conventional medical care.
Given that cannabinoids have anti-inflammatory properties, they may be able to aid athletes—particularly those who are recuperating from injuries—relieve pain, swelling, and inflammation. Because it has anti-inflammatory and pain-relieving effects, CBD may offer certain athletes a safer alternative to NSAIDs.